Sunday, March 15, 2015
Signs and Symptoms Associated with Down Syndrome
Down syndrome is the most common autosomal trisomy identified in liveborn infants. As many as 95% of Down syndrome cases arise due to chromosomal nondisjunction during maternal meiosis (47 XX, +21) an abnormality that positively correlates with increasing maternal age. Two of the more prominent and consistent lectures of Down syndrome are mental retardation and facial dysmorphism. Almost every organ and system, however, is affected
Signs and Symptoms Associated with Down Syndrome
Trisomy 21 (Down syndrome) is characterized by mental retardation, facial dysmorphism, single palmar crease, endocardial cushion defects, and duodenal atresia. Affected individuals have an increased risk of AML-M7 and ALL in childhood and early Alzheimer disease in adulthood.
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